February, 2012 Edition

Welcome to the monthly newsletter of the Buffalo Clinical and Translational Research Center. The purpose of the newsletter is to update leadership, faculty, trainees, and community partners of the Buffalo Translational Consortium on activities.

Message from the CTRC Director

The opening of the CTRC building in May is fast approaching. The Grand Opening will be September 20 and will include public events with academic and community leaders and a half day scientific symposium with a keynote speaker. Stay tuned for details.

Timothy F. Murphy MD
Director, Buffalo Clinical and Translational
Research Center

Featured Key Function: Regulatory Knowledge and Support

Director: Kenneth M. Tramposch, PhD

  • Associate Vice President for Research
  • Associate Professor of Pharmacology and Toxicology Research

The goal of the Regulatory Knowledge and Support key function is to provide an array of services and educational opportunities to allow researchers to be fully compliant with regulations when conducting studies with human subjects.

Two recent developments will advance clinical research in Buffalo significantly:

1. Implementation of online submission of IRB applications using the web based tool called IRBNet. IRBNet offers several excellent features:

  • Ease of use
  • Cost effectiveness
  • Instantaneous approval notification
  • Improved quality of the project documentation
  • Interoperability with all SUNY Academic Health Centers

Through the SUNY REACH initiative, a single IRB review will be accepted by all of the SUNY Academic Health centers significantly streamlining the review process and facilitating enrollment of subjects in multicenter trials.

2. Supporting the development of a Consortium to Accelerate Therapeutic Applications of Stem Cells in response to an RFA from the Empire State Stem Cell Board and the NYS Department of Health. This proposal, led by Dr. John Canty, UB Chief of Cardiovascular Medicine uses stem cells to improve cardiac function.

Dr. Ken Tramposch of the Regulatory Core has had pre-IND interactions with the FDA in helping to develop the regulatory path for this translational research project. This project will use an approach to manufacturing of clinical supplies that will be fully compliant with cGMPs. This approach will have a major impact on minimizing the cost of early trials while still meeting approval by the FDA.

CTRC Building Update

Sixth Floor: View of the atrium from sixth floor bridge

Construction continues with a projected completion in May. Installation of the paneling on the south wall of the atrium, which spans the fifth through eighth floors, is nearly complete. Construction of the café on the fifth floor has begun.


Left Photo: Café area of the fifth floor;
Right Photo
: Exam room in the Clinical Research Center

NEWS UPDATES & UPCOMING EVENTS

A ribbon cutting for the UB Clinical and Translational Research Center and the Kaleida Gates Vascular Institute is scheduled for May 24. A Grand Opening and Open House for the CTRC will take place on September 20.

Click for info about the UB Kaleida partnership and a video of the CTRC
Click for info about ongoing and upcoming CTRC initiatives

As part of a broad-based initiative to expand and improve training in clinical research for researchers and trainees in the Buffalo Translational Consortium, the UB School of Public Health and Health Professions is offering graduate training that will lead to an MS in Epidemiology with a concentration in Clinical Research. The program can be individualized to suit the needs of many trainees.

Click for more info about the Graduate Program in Clinical Research
Click for more details about the Epidemiology program

The UB Research Institute on Addictions held a reception on February 9 to honor Dr. Gerard Connors who is stepping down as Director after a highly successful 13-year tenure. He will continue to direct his NIH funded research program at the RIA.

UB President Dr. Satish Tripathi recognized Dr. Connors’ outstanding contributions and also welcomed Dr. Kenneth Leonard, a nationally recognized researcher in addictions, and the new Director. As Director of the RIA, Dr. Leonard has joined the Governing Board of the CTRC.

Click here for more details and a biography of Dr. Leonard

Marsha Lewis PhD RN, formerly associate professor and associate dean for education in the Nell Hodgson Woodruff School of Nursing at Emory University in Atlanta, assumed leadership of the School of Nursing this month. Dr. Lewis is an expert in psychiatric-mental health and nursing education and conducts a research program for caregivers of persons with dementia. She succeeds Dr. Davina Porock who served as Interim Dean and continues as associate dean for research and scholarship.

As Dean of the School of Nursing Dr. Lewis will join the Governing Board of the CTRC.

Click for details of Dr. Lewis’s appointment and a biography

The series continues every Wednesday from 5:30 to 6:30 PM. The fourth of four sessions on Biomedical Informatics will be on February 29 when Drs. Kinga Szigeti and Barry Smith will present a case study in information-driven research on Alzheimer's disease.

Sessions on drug development, regulatory issues in clinical research and teamwork in translational research will follow the biomedical informatics block.

Click for titles of the sessions, location and other details at the School of Medicine calendar
Click for slides of each of the seminars