Dr. Mark Hicar Moves his Laboratory into CTRC
Mark Hicar MD PhD, Assistant Professor of Pediatrics in the Division of Pediatric Infectious Diseases, has moved his laboratory into the CTRC. Dr. Hicar came to Buffalo approximately one year ago from Vanderbilt University where he completed his fellowship training and stayed on as an attending physician. His laboratory studies immune responses to HIV and cytomegalovirus. His work is supported by an NIH K08 Mentored Clinical Scientist Research Career Development Award.
Read his biographical sketch and research interests.
Mark Hicar MD PhD, Assistant Professor of Pediatrics
Dermatology Team Identifies a Novel "Protection Signature" for Autoimmune Disease
Dr. Animesh Sinha and his team have recently published a key new observation that has broad-ranging implications in understanding susceptibility to autoimmune disorders. Using state-of-the-art methods, Dr. Sinha and colleagues developed the first genome-wide transcriptional analysis of the blistering autoimmune condition, pemphigus vulgaris. The work was performed with Drs. Rama Dey-Rao and Kristina Seiffert-Sinha in the Dermatology laboratories in the CTRC.
See here for a more detailed story.
See the abstract of the article here.
Animesh Sinha MD PhD, Rita M. and Ralph T. Behling Professor and Chair of Dermatology
Study by Dr. Thomas Cimato Identifies Link Between Stem Cells and Cholesterol
In a study that makes a critical link between animal studies and humans, Dr. Thomas Cimato and his colleagues demonstrated that elevated cholesterol recruits stem cells from the bone marrow into the bloodstream through increases in the cytokine interleukin-17. This observation will lead to new lines of investigation to develop novel therapies to prevent cardiovascular disease. Dr. Thomas Cimato is Assistant Professor of Medicine. Beth Palka, senior research support specialist, Dr. Jennifer Lang, cardiology fellow and Rebeccah Young, research scientist, contributed to the work performed in the cardiovascular Research Laboratories in the CTRC.
Read more about this work here.
The article, published in the open access journal PLOS ONE, is available here.
Dr. Thomas Cimato in his laboratory in the CTRC